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Beilstein J. Org. Chem. 2012, 8, 2004–2018, doi:10.3762/bjoc.8.227
Graphical Abstract
Figure 1: Representative drug candidates of amino-azaindole and phenyl-azaindole containing motifs.
Scheme 1: Cross coupling of 4-bromo-7-azaindole with amides, amines, amino acid esters and phenols.
Beilstein J. Org. Chem. 2010, 6, 1174–1179, doi:10.3762/bjoc.6.134
Scheme 1: Lipase-catalyzed acetylation of racemic benzylic secondary alcohol [(RS)-4] and its application.
Scheme 2: FeCl3-meditated synthesis of bis-imines.
Scheme 3: Preparation of racemic 3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate [(RS)-4]
Scheme 4: Proposed reaction mechanism of lipase-catalyzed acetylation of racemic alcohol 4.
Scheme 5: Complete synthesis of rivastigmine.